AmaZulu have found themselves stuck second from bottom of the Absa Premiership log following the 2-1 defeat by Bidvest Wits on Friday.
Second half goals from Rowan Human and Deon Hotto secured maximum points for the Students who now move to fourth position.
Usuthu pulled one back through Lehlohonolo Majoro late in the game but it was too little too late as they now find themselves a point above bottom placed Polokwane City, with four matches remaining.
In the other Absa Premiership result on Friday, Black Leopards won 2-1 against Golden Arrows.
By Ofhani Munyai